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POLISEPT® VET
WOUND IRRIGATION

Isotonic formulation in a lotion form for all kinds of wounds, and the preparation of the wound bed for further therapeutic measures.

Polisept® Vet Wound Irrigation is a modern preparation used in the care and helping heal wounds in animals.

Polisept® Vet Wound Irrigation comprises two synergistically acting active ingredients in an iso-osmotic Ringer

  • Polyhexanide (PHMB): biguanide agent with a broad spectrum of activity against pathogenic microbes.
  • Betaine (tenside): mild surfactant, effectively removes mechanical and biological impurities including BACTERIAL BIOFILM.

Indications and application Properties of Compatibility with the scheme “Time”

INDICATIONS AND APPLICATION PROCEDURE

Polisept® Vet Wound Irrigation is used in adjunctive treatment of:

  • Surgical wounds
  • Acute sterile and infected wounds (including recesses and pockets)
  • Chronic wounds (decubitus ulcers, ulcerations), including infected wounds
  • Local burns of I and II degree
  • Pressure ulcers, abscesses and ulcerations

and:

  • Intraoperative wound protection
  • Removal of dried up dressings

 

APPLICATION PROCEDURE:

 

1

 
Direct application to the wound, wound irrigation
Wounds can be flushed by pouring the liquid directly from the packaging (Fig. 1) or with a syringe with a cannula or thick needle. In the case of bite wounds and lacerations or in the presence of recesses and pockets, the drainage of fluid from the wound should be provided. The fluid should not enter into the wound under high pressure. It is recommended, especially in the management of chronic wounds, to heat the liquid to a temperature close to physiological body temperature (do not use cold fluid taken out of the refrigerator). For further procedures, i.e. the use of other drugs, the wound should be dried, e.g. with sterile pad.

 

 

2

 
Application of moistened compresses.
Place wetted, heated with fluid compress on the wound, gently press and leave for 10-15 minutes. Prepare lotion by moisturizing sterile gauze or compresses in a ratio of 10 ml. of liquid for 10×10 cm2 of gauze / compress (Fig. 2, 2a). This method is recommended especially in handling of chronic infected wounds for effective removal of bacterial biofilm. The dressing can be prepared in a similar way. It should be changed with a frequency appropriate to the nature.

 

 

 

3

 
Wiping wounds.
Dead tissue, dirt, mechanical and biological properties can also be removed by gentle wiping of the surface of the wound with gauze or a compress abundantly soaked with heated fluid (Fig. 3).

 

 

 

4

 
Removing dried up dressings.
Dried up dressing should be intensely dampened with the heated fluid (Fig. 4), wait until the dressing can be gently removed so as not to damage the wound. After removing the dressing, the wound can be covered with a humidified compress left (Fig. 4a) for 10-15 minutes in order to get better cleaning of the wound from possible organic residues.

 

FEATURES

POLISEPT® VET WOUND IRRIGATION:

1

Efficiently removes mechanical and biological impurities

2

Precisely penetrates and purifies pockets and recesses of wounds ( bite wounds and lacerations)

3

Efficiently removes bacterial biofilm

4

Efficiently prevents biofilm formation

5

Eliminates or significantly reduces the risk of the spread of infection induced by transmission of microorganisms from a wound on the adjacent tissue.

 

 

 

6

Presents excellent tissue tolerance (very low cellular toxicity, lack of allergenic activity)

7

Speeds up wound healing, has a wide range of applications ( “TIME”, Lavaseptics)

8

Perfectly fits into the scheme of “TIME” for dealing with wounds

9

Allows effective and non-invasive removal of dressings

 

 

 

 

The unique properties of Polisept® Vet Wound Irrigation result from the synergistic action of the main active substance, antibacterial agent and the surfactant contained in the Ringer solution.

 

 


Antibacterial agent Polyhexanide (PHMB)

  • broad antibacterial spectrum:
    Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus faecalis, Escherichia coli, Pseudomonas putida, Klebsiella aerogenes including high efficacy against MRSA (methicillin-resistant Staphylococcus aureus)
  • antifungal Activity: i.e. Aspergillus Niger, Trichophyton mentagrophytes
  • lack of development of microbial resistance
  • anti-inflammatory
  • index of biocompatibility B>1 (high antimicrobial activity and low cytotoxicity)
  • lack of allergenic activity (index of 1:10 000)

 

The mechanism of PHMB.

Polyhexanide has affinity for cell membranes of microorganisms. Interacting with the membrane proteins it neutralizes their immune system and penetrates inside the bacterial cell. Then it combines with the cytoplasmic membrane proteins resulting in a loss of Mg and Ca ions, with consequent disruption of the cytoplasmic membrane of the bacterial cell. In this step of PHMB, the process is irreversible and leads to the death of the bacterial cell by loss of essential morphotic elements.

Because of its broad and specific properties, PHMB is recommended as a treatment of choice in the handling of slow healing chronic wounds.

 


 

 

Betaine (Tenside)

  • gently operating surfactants
  • seffectively removes biological contaminants including BACTERIAL BIOFILM
  • effectively removes mechanical impurities from within the wound
  • very good skin tolerance
  • it does not have a drying action on the skin and mucous membranes

 

The mechanism of action of Betaine.

Betaine is a mild surfactant, highly effective in wound irrigation. The mechanism of action of betaine involves the lowering of the surface tension of the liquid phase, which leads to the separation of organic substances from the base (micro-organisms, tissue necrosis, etc.), and inorganic substances. It also prevents re-merging of isolated elements into aggregates or re-attachment of microorganisms to the wound surface, thus effectively affects the flushing of any “contamination” from the wound. A special characteristic of betaine includes the ability to destroy the integrity of the bacterial BIOFILM within the wound, leading to the exposure of microbes to e.g. antibiotics. Bacterial biofilm is a major obstacle in the treatment of chronic wounds (observed in more than 60% of chronic wounds) and acute wounds in the early hours of treatment.

 


 

 

Ringer solution

  • very well tolerated by the tissues, much better tolerance than in the case of traditional saline solution

 

 

  • due to the real iso-osmotic nature of multi-electrolyte Ringer Solution, its use prevents irritation within the wound and swelling of the adjacent skin

 


 

 

 

 

COMPATIBILITY WITH TIME

Liquid Polisept® Vet Wound Irrigation is a product that gives excellent results in the management of wounds, conducted within the scheme of TIME. It can be used at all stages of the proceedings according to TIME, but it best fits into points T and I of scheme.

Specific applications are found in lavaseptics, for irrigation of wounds under the Protocol of BBWC scheme TIME.

 

 

 

 

 

POLISEPT® VET
WOUND GEL

Active dressing in the form of a hydrocolloid gel to be used for all kinds of wounds.

Polisept® Vet Wound Gel is a modern preparation used in the care and helping heal wounds in animals.

Polisept® Vet Wound Gel contains two synergistically acting active substances contained in the hydrocolloid gel:

  • Polyhexanide (PHMB): biguanide agent with a broad spectrum of activity against pathogenic microbes
  • Betaine (tenside): mild surfactant, effectively removes mechanical and biological impurities including BACTERIAL BIOFILM

Indications and application Properties of Compatibility with the scheme “Time”

INDICATIONS AND APPLICATION PROCEDURE

Polisept® Vet Wound Gel is used in adjunctive treatment for:

  • Surgical wounds
  • Acute infected and sterile wounds
  • Chronic wounds (pressure ulcers, ulcerations of various origin)
  • Wounds with dry or epidermal necrosis
  • Superficial and deep wounds (lacerations, bite wounds with recesses and pockets)
  • Burns of I and II degree

 

APPLICATION PROCEDURE:

 

 

1

 
Before using the gel, it is recommended to clean and decontaminate the wound using a fluid for irrigation of wounds Polisept® Vet Wound Irrigation (depending on the type and condition of the wound) (Fig. 1), or if necessary, apply surgical treatment of the wound.
Removal of mechanical and biological impurities and decontamination of wound including removal of bacterial Biofilm creates optimal conditions for further treatment. Sparging lacerations, bite wounds, recesses or pockets must ensure the drainage of fluid. The gel must be applied on the dried wound. Severe infection of the wound may require application of suitable antiseptic formulation.

 

 

2

 
Gel application.
By squeezing the tube, apply a thin layer (3-5 mm) directly on the wound (Fig. 2)
The gel can also be applied to a wound with a sterile spatula (Fig. 3, 3a)
In the case of deep wounds, fill the wound with gel to 2/3 of the depth so as not to leave it protruding above the surface of the skin surrounding the wound.
The wound should be covered with a secondary dressing (in the case of the daily exchange gel in the wound, you do not need to use secondary dressings however, it should be protected against licking by the animal).

 

 

 

 

 

3

 
Secondary dressings.
All types of secondary dressings. Gauze, compresses or other easily absorbable dressings should also be soaked with the preparation (Fig. 4)

 

 

 

 

 

4

 
Change of dressing.
The frequency of dressing changes depends on the adopted procedure, nature and condition of the wound. The gel can be changed every day (Fig. 5) or left in the wound for 3 days. When changing the dressing, remove gently the gel residues or other residues (so as not to damage the wound) rinse the wound with irrigation fluid Polisept® Vet Wound Gel (Fig. 5, 6, 6a) based on the condition of the wound.

 

PROPERTIES OF

POLISEPT® VET WOUND GEL:

1

Speeds up and facilitates the process of wound healing

2

Provides optimum water balance within the wound

3

Cleans the wound from biological contamination arising during wound healing (waste products, toxins, etc.).

4

Protects the wound against external infection while ensuring optimal gas exchange

 

 

 

5

Prevents biofilm formation

6

Speeds up angiogenesis within the wound

7

Perfectly fits into the scheme of “TIME” for dealing with wounds

 

 

POLISEPT® VET WOUND GEL:

  • Effectively moisturizes the wound and regulates the exchange of water and gas in the wound
  • Adsorbs wound exudate
  • Effectively removes inorganic contaminants, mechanical and organic impurities, necrotic tissue, fibrin fibers, blood clots

 

The unique properties of Polisept® Vet Wound Gel result from the synergistic action of the main active substance, antibacterial agent and tenside contained in the hydrocolloid gel.

 

 

 

 


Antibacterial agent Polyhexanide (PHMB)

  • broad antibacterial spectrum:
    Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus faecalis, Escherichia coli, Pseudomonas putida, Klebsiella aerogenes including high efficacy against MRSA (methicillin-resistant Staphylococcus aureus)
  • antifungal Activity: i.e. Aspergillus Niger, Trichophyton mentagrophytes
  • lack of development of microbial resistance
  • anti-inflammatory
  • index of biocompatibility B>1 (high antimicrobial activity and low cytotoxicity)
  • lack of allergenic activity (Index of 1:10 000)

 

The mechanism of PHMB.

Polyhexanide has affinity for cell membranes of microorganisms. Interacting with the membrane proteins it neutralizes their immune system and penetrates inside the bacterial cell. Then it combines with the cytoplasmic membrane proteins resulting in a loss of Mg and Ca ions, with consequent disruption of the cytoplasmic membrane of the bacterial cell. In this step of PHMB, the process is irreversible and leads to the death of the bacterial cell by loss of essential morphotic elements.

Because of its broad and specific properties, PHMB is recommended as a treatment of choice in the handling of slow healing chronic wounds.

 


 

 

Betaine (Tenside)

  • gently operating surfactants
  • effectively removes biological contaminants including BACTERIAL BIOFILM
  • effectively removes mechanical impurities from within the wound
  • very good skin tolerance
  • it does not have a drying action on the skin and mucous membranes

 

The mechanism of action of Betaine.

Betaine is a mild surfactant, highly effective in wound irrigation. The mechanism of action of betaine involves the lowering of the surface tension of the liquid phase, which leads to the separation of organic substances from the base (micro-organisms, tissue necrosis, etc.), and inorganic substances. It also prevents re-merging of isolated elements into aggregates or re-attachment of microorganisms to the wound surface, thus effectively affects the flushing of any “contamination” from the wound. A special characteristic of betaine includes the ability to destroy the integrity of the bacterial BIOFILM within the wound, leading to the exposure of microbes to e.g. antibiotics. Bacterial biofilm is a major obstacle in the treatment of chronic wounds (observed in more than 60% of chronic wounds) and acute wounds in the early hours of treatment.

 


 

 

Hydrocolloid gel
It provides the right conditions of wound humidity – maintains the optimum humidity within the wound

 

  • moisturizes too dry wounds
  • removes excess of mucus in the too wet wounds

 

 

  • creates an antimicrobial barrier to protect the wound
  • It is very well tolerated by the tissues

 


 

 

 

 

COMPATIBILITY WITH TIME

Polisept® Vet Wound Gel is a product that gives excellent results in the management of wounds, conducted within the scheme TIME, meeting the requirements set out in sections M and E

 

 

 

 

 

POLISEPT® VET
SPRAY

is a preparation intended for antiseptic procedures connected with wound, mucosa and damaged skin

Polisept® Vet Spray is a modern preparation applied in taking care and facilitating treatment of wounds in animals.

Polisept® Vet Spray contains active substances with synergic effect included in hydrocolloid gel:

  • Polyhexanide (PHMB): biguanide agent with a wide spectrum of effect contra pathogenic microbes
  • Betaine (tenside): gentle surface active agent effectively removing mechanical and biological contamination, including BACTERIAL BIOFILM

Indications and application Properities of

INDICATIONS AND APPLICATION PROCEDURE

Polisept® Vet Spray for procedures concerning wounds and damaged skin, applied to:

  • cleansing and disinfection of infected wounds, abscesses, ulcers, bite wounds, cuts
  • protecting wounds from infection
  • cleaning and protecting surgical wounds
  • taking care of wounds upon surgical procedures, including surgical stitches
  • proceeding with focal burns of 1st and 2nd degree
  • everyday hygiene of traumatic or surgical wounds
  • non-invasive removal of dried up dressings

 

APPLICATION PROCEDURE:

 

1

 
Apply the preparation on the wound and surrounding tissues directly from the container by pressing the applicator repeatedly (according to the need). In case of bite wounds, flow of fluid from the wound must be ensured. Depending on the wound condition, repeat these actions a few times during a day (2-4 times).
In everyday hygiene of the wound and care of post-operative wounds and surgical stitches, apply the preparation directly on the wound. Repeat these actions a few times during a day.
In case of wounds showing signs of severe infection and inflammatory condition, wet dressings can be applied in the form of moistened compresses.

 

 

 

 

 

 

2

 
Application of moistened compresses.
Cover the wound with a moistened compress, press delicately and leave for 10-15 minutes. This method is especially recommended in proceeding with chronic, infected wounds in order to effectively remove the bacterial biofilm.

 

 

 

3

 
Removal of dried up dressings.
Abundantly moisten the dried-up dressing with warmed Polisept® Vet Spray, fluid, wait until the dressing can be gently removed without damaging the wound (as a rule, the dressing can be easily removed after a few minutes).

 

 

PROPERTIES

POLISEPT® VET SPRAY:

1

Fights bacterial infection of the wound, including MRSA, VRE, ESBL

2

Removes bacterial biofilm and prevents its creation

3

Eliminates inflammatory condition

4

Protects wounds from external infection

 

 

 

5

Provides optimum conditions for regenerative processes in the wound

6

Facilitates the process of wound healing and prevents scar formation

7

Reduces pain within the wound

 

 

POLISEPT® VET Spray

The special properties of Polisept® Vet Spray preparation result only from combination of active substances with synergy effect: Polyhexanides (PHMB) with anti-microbial effect and betaines – surface active substances, effectively facilitate removal of all types of mechanical and biological contamination, including bacterial biofilm.

 

 

  • Strong anti-microbial effect
  • Anti-inflammatory properties
  • Analgesic effect – pain reduction in the injury site
  • Lack of development of microbial resistance to PHMB
  • Long-term therapeutic effect upon application

 

 


Effectiveness

  • wide anti-bacterial spectrum :
    Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus faecalis, Escherichia coli, Pseudomonas putida, Klebsiella aerogenes, high efficiency in relation to MRSA (Staphylococcus aureus stains resistant to methicillin)
  • antifungal effect, including Aspergillus Niger, Trichophyton mentagrophytes
  • lack of development of microbial resistance
  • anti-inflammatory properties
  • biocompatibility index B>1 (high anti-microbial activity and low cytotoxicity)
  • lack of allergenic effect (index 1:10 000)

 

Safety

  • very favourable biocompatibility index B>1
    (high anti-microbial activity and low cytotoxicity)
  • lack of mutagenic and teratogenous properties
  • lack of systemic absorption from the application site
  • lack of allergenic effect
    (local allergic reactions occur very rarely – index 1:10000)
  • does not cause skin and mucosa drying

 


 

 

POLISEPT® VET AL
Alginate Wound Dressing

Dressing is a direct sterile dressing, containing calcium alginate, that comes in the form of flat plates.

INDICATIONS & ACTIONS DIRECTIONS OF USE

MECHANISM OF ACTION

Calcium alginate has high absorption properties. When in contact with wound secretions, the calcium alginate fibres transform into a gentle gel which fills the wound bed. The resultant gel creates the ideal environment for the healing of the wound: optimal moisture levels that improve granulation and epidermal processes, ensures thermal insulation, ensures mechanical isolation that protects the wound from outside infection while not interfering with gas exchange.

 

INDICATIONS

POLISEPT® VET AL is an absorbent dressing and can be used for both shallow and deep, penetrating wounds.
Wound exudate level: abundant or medium.

DIRECTIONS OF USE

 

 

1

 
Rinse the wound with Polisept® Vet Wound Irrigation or Polisept® Vet Spray

 

2

 
Dry the skin around the wound, but lightly moisten the wound bed itself.

 

3

 
Adjust the size of the dressing such that it covers the entire surface of the wound. Leave an additional 2 cm margin.

 

4

 
Place the POLISEPT® VET AL directly on the wound. In the case of deep wounds, they can be filled with an appropriately cut amount of dressing.

 

5

 
Cover the alginate dressing with an additional external dressing (to be secured with either a bandage or plaster).
POLISEPT® VET AL should be used until wound secretions are minimal or stop altogether.

 

DIRECTIONS OF USE - POLISEPT® VET AL Alginate Wound Dressing

POLISEPT® VET AL/AG
Silver Alginate Wound Dressing

is a direct sterile dressing, containing calcium alginate enriched with silver ions, that comes in the form of flat plates.

INDICATIONS & ACTIONS DIRECTIONS OF USE

MECHANISM OF ACTION

Calcium alginate has high absorption properties, and silver ions have antibacterial properties. When in contact with wound secretions, the calcium alginate fibres transform into a gentle gel which fills the wound bed, while the silver ions are simultaneously released into the wound and act in a bactericidal manner. The resultant gel creates the ideal environment for the healing of the wound: optimal moisture levels that improve granulation and epidermal processes, ensures thermal insulation, and ensures mechanical isolation that protects the wound from external environmental stressors while not interfering with gas exchange. Silver ions fight infection within the wound and prevent external infection.

 

INDICATIONS

POLISEPT® VET AL/AG is an absorbent dressing with aseptic properties that can be used for both shallow and deep, penetrating wounds, be it infected or clean.
Wound exudate level: abundant or medium.

DIRECTIONS OF USE

 

 

1

 
Rinse the wound with Polisept® Vet Wound Irrigation or Polisept® Vet Spray

 

2

 
Dry the skin around the wound, but lightly moisten the wound bed itself.

 

3

 
Adjust the size of the dressing such that it covers the entire surface of the wound. Leave an additional 2 cm margin.

 

4

 
Place the POLISEPT® VET AL/AG Dressing directly on the wound. In the case of deep wounds, they can be filled with an appropriately cut amount of dressing.

 

5

 
Cover the POLISEPT® VET AL/AG with an additional external dressing (to be secured with either a bandage or plaster).
During the initial treatment period for an infected wound, the POLISEPT® VET AL/AG should be changed daily, after which depending on the degree of severity of the infection, the dressing should be used until wound secretions are minimal or stop altogether.

 

DIRECTIONS OF USE - POLISEPT® VET AL/AG Silver Alginate Wound Dressing

POLISEPT® VET H
Hydrocolloid Wound Dressing

is a direct sterile dressing that contains a hydrocolloid layer covered in a semi-permeable film. The dressing ensures that the wound remains isolated and creates and maintains a balanced moist environment that is ideal for granulation and epidermal processes.

INDICATIONS & ACTIONS DIRECTIONS OF USE

MECHANISM OF ACTION

Upon contacting the wound exudate, the hydrocolloid layer of the dressing increases in volume and hence forms a soft yellowish gel under which the healing process takes place. When the time comes for a dressing change, it is easy to remove without trauma or pain.

 

INDICATIONS

  • shallow wounds with yellow, diffuse necrotic tissue
  • wounds in the granulation phase and early epidermal process phase
  • bedsores
  • chronic wounds that have difficulty healing

Wound exudate level: minimal or medium.

DIRECTIONS OF USE

 

 

1

 
Rinse the wound with Polisept® Vet Wound Irrigation Solution or Polisept® Vet Spray, if necessary (in the case of necrosis, the necrotic layers should be removed before applying the dressing).

 

2

 
Dry the skin around the wound.

 

3

 
Adjust the size of the dressing such that it covers the entire surface of the wound. Leave an additional 2-3 cm margin (if a large wound needs to be covered, several overlapping dressings can be applied).

 

4

 
Place the POLISEPT® VET H Dressing directly on the wound and gently press down the edges of the dressing.

 

DIRECTIONS OF USE - POLISEPT® VET H Hydrocolloid Wound Dressing
POLISEPT VET Recovery

POLISEPT® VET Recovery

Lack of energy? Weak after injuries or surgical procedures?
This product delivers substances providing energy to improve the physical condition of animals.

INDICATIONS & ACTIONS DIRECTIONS OF USE

MECHANISM OF ACTION

The Polisept® Vet Recovery dietary supplement is used preventively and to strengthen the animals weakened e.g. after complicated surgical procedures, injuries, during recovery after malignant diseases, as well as for sports or hard-working animals for which easily absorbable energy substances with a long-term effect needs to be supplemented.

Glucose covers about 60 % of energy demands and is the main and almost the only source of energy for the central nervous system. Administration of a properly composed sugar syrup containing easily absorbable monosaccharides (glucose, fructose) in an energy deficiency state allows for a rapid and effective replenishment of the necessary energy needed to maintain endangered metabolic processes.

While the sucrose content, which is a disaccharide composed of one glucose molecule and one fructose molecule, provides a prolonged effect of action and allows for the regeneration of consumed energy.

DIRECTIONS OF USE

Administer the product directly into the mouth.

Daily dose – 1 full tube.

Preventive dosage:
(sports or hard-working animals)
1 tube / 25 kg of body weight once a day.
Supportive treatment dosing:
(energy deficient animals)
1 tube / 15 kg of body weight once a day.