Polisept® Vet wound irrigation

POLISEPT® VET
WOUND IRRIGATION

Isotonic formulation in a lotion form for all kinds of wounds, and the preparation of the wound bed for further therapeutic measures.

Polisept® Vet Wound Irrigation is a modern preparation used in the care and helping heal wounds in animals.

Polisept® Vet Wound Irrigation comprises two synergistically acting active ingredients in an iso-osmotic Ringer

  • Polyhexanide (PHMB): biguanide agent with a broad spectrum of activity against pathogenic microbes.
  • Betaine (tenside): mild surfactant, effectively removes mechanical and biological impurities including BACTERIAL BIOFILM.

Indications and applicationProperties of Compatibility with the scheme “Time”

INDICATIONS AND APPLICATION PROCEDURE

Polisept® Vet Wound Irrigation is used in adjunctive treatment of:

  • Surgical wounds
  • Acute sterile and infected wounds (including recesses and pockets)
  • Chronic wounds (decubitus ulcers, ulcerations), including infected wounds
  • Local burns of I and II degree
  • Pressure ulcers, abscesses and ulcerations

and:

  • Intraoperative wound protection
  • Removal of dried up dressings

 

APPLICATION PROCEDURE:

 

1

 
Direct application to the wound, wound irrigation
Wounds can be flushed by pouring the liquid directly from the packaging (Fig. 1) or with a syringe with a cannula or thick needle. In the case of bite wounds and lacerations or in the presence of recesses and pockets, the drainage of fluid from the wound should be provided. The fluid should not enter into the wound under high pressure. It is recommended, especially in the management of chronic wounds, to heat the liquid to a temperature close to physiological body temperature (do not use cold fluid taken out of the refrigerator). For further procedures, i.e. the use of other drugs, the wound should be dried, e.g. with sterile pad.

 

 

2

 
Application of moistened compresses.
Place wetted, heated with fluid compress on the wound, gently press and leave for 10-15 minutes. Prepare lotion by moisturizing sterile gauze or compresses in a ratio of 10 ml. of liquid for 10×10 cm2 of gauze / compress (Fig. 2, 2a). This method is recommended especially in handling of chronic infected wounds for effective removal of bacterial biofilm. The dressing can be prepared in a similar way. It should be changed with a frequency appropriate to the nature.

 

 

 

3

 
Wiping wounds.
Dead tissue, dirt, mechanical and biological properties can also be removed by gentle wiping of the surface of the wound with gauze or a compress abundantly soaked with heated fluid (Fig. 3).

 

 

 

4

 
Removing dried up dressings.
Dried up dressing should be intensely dampened with the heated fluid (Fig. 4), wait until the dressing can be gently removed so as not to damage the wound. After removing the dressing, the wound can be covered with a humidified compress left (Fig. 4a) for 10-15 minutes in order to get better cleaning of the wound from possible organic residues.

 

FEATURES

POLISEPT® VET WOUND IRRIGATION:

1

Efficiently removes mechanical and biological impurities

2

Precisely penetrates and purifies pockets and recesses of wounds ( bite wounds and lacerations)

3

Efficiently removes bacterial biofilm

4

Efficiently prevents biofilm formation

5

Eliminates or significantly reduces the risk of the spread of infection induced by transmission of microorganisms from a wound on the adjacent tissue.

 

 

 

6

Presents excellent tissue tolerance (very low cellular toxicity, lack of allergenic activity)

7

Speeds up wound healing, has a wide range of applications ( “TIME”, Lavaseptics)

8

Perfectly fits into the scheme of “TIME” for dealing with wounds

9

Allows effective and non-invasive removal of dressings

 

 

 

 

The unique properties of Polisept® Vet Wound Irrigation result from the synergistic action of the main active substance, antibacterial agent and the surfactant contained in the Ringer solution.

 

 


Antibacterial agent Polyhexanide (PHMB)

  • broad antibacterial spectrum:
    Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus faecalis, Escherichia coli, Pseudomonas putida, Klebsiella aerogenes including high efficacy against MRSA (methicillin-resistant Staphylococcus aureus)
  • antifungal Activity: i.e. Aspergillus Niger, Trichophyton mentagrophytes
  • lack of development of microbial resistance
  • anti-inflammatory
  • index of biocompatibility B>1 (high antimicrobial activity and low cytotoxicity)
  • lack of allergenic activity (index of 1:10 000)

 

The mechanism of PHMB.

Polyhexanide has affinity for cell membranes of microorganisms. Interacting with the membrane proteins it neutralizes their immune system and penetrates inside the bacterial cell. Then it combines with the cytoplasmic membrane proteins resulting in a loss of Mg and Ca ions, with consequent disruption of the cytoplasmic membrane of the bacterial cell. In this step of PHMB, the process is irreversible and leads to the death of the bacterial cell by loss of essential morphotic elements.

Because of its broad and specific properties, PHMB is recommended as a treatment of choice in the handling of slow healing chronic wounds.

 


 

 

Betaine (Tenside)

  • gently operating surfactants
  • seffectively removes biological contaminants including BACTERIAL BIOFILM
  • effectively removes mechanical impurities from within the wound
  • very good skin tolerance
  • it does not have a drying action on the skin and mucous membranes

 

The mechanism of action of Betaine.

Betaine is a mild surfactant, highly effective in wound irrigation. The mechanism of action of betaine involves the lowering of the surface tension of the liquid phase, which leads to the separation of organic substances from the base (micro-organisms, tissue necrosis, etc.), and inorganic substances. It also prevents re-merging of isolated elements into aggregates or re-attachment of microorganisms to the wound surface, thus effectively affects the flushing of any “contamination” from the wound. A special characteristic of betaine includes the ability to destroy the integrity of the bacterial BIOFILM within the wound, leading to the exposure of microbes to e.g. antibiotics. Bacterial biofilm is a major obstacle in the treatment of chronic wounds (observed in more than 60% of chronic wounds) and acute wounds in the early hours of treatment.

 


 

 

Ringer solution

  • very well tolerated by the tissues, much better tolerance than in the case of traditional saline solution

 

 

  • due to the real iso-osmotic nature of multi-electrolyte Ringer Solution, its use prevents irritation within the wound and swelling of the adjacent skin

 


 

 

COMPATIBILITY WITH TIME

Liquid Polisept® Vet Wound Irrigation is a product that gives excellent results in the management of wounds, conducted within the scheme of TIME. It can be used at all stages of the proceedings according to TIME, but it best fits into points T and I of scheme.

Specific applications are found in lavaseptics, for irrigation of wounds under the Protocol of BBWC scheme TIME.